Human Amiloride-sensitive amine oxidase [copper-containing], ABP1 ELISA Kit (ELISA Kit)

SynName: amine oxidase copper domain-containing protein 1; *amiloride binding protein 1 (amine oxidase (copper-containing)); amine oxidase, copper containing 1; *Amiloride-binding protein 1; Amine oxidase copper domain-containing protein 1; Histaminase; *Specificity: This assay has high sensitivity and excellent specificity for detection of Human ABP1. No significant cross-reactivity or interference between Human ABP1 and analogues was observed.Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV% is less than 8% Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision (Precision between assays): CV% is less than 10% Three samples of known concentration were tested in twenty assays to assess.; *Storage: Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.; *Accession#: NP_001082.2; NM_001091.3; P19801; *NCBI Summary: This gene encodes a metal-binding membrane glycoprotein that oxidatively deaminates putrescine, histamine, and related compounds. The encoded protein is inhibited by amiloride, a diuretic that acts by closing epithelial sodium ion channels. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2013]; *Uniprot Summary: Function: Catalyzes the degradation of compounds such as putrescine, histamine, spermine, and spermidine, substances involved in allergic and immune responses, cell proliferation, tissue differentiation, tumor formation, and possibly apoptosis. Placental DAO is thought to play a role in the regulation of the female reproductive function.Catalytic activity: Histamine + H2O + O2 = (imidazol-4-yl)acetaldehyde + NH3 + H2O2.Cofactor: Binds 1 copper ion per subunit.1 PublicationManual assertion based on experiment in:Ref.8