Genuine Nightingale Droppings "Uguisu No Fun" Facial Care Powder - 20 grams

Original Japanese traditional formula. Geishas and Kabuki actors have been using Uguisu-no-Fun for a very long time to brighten and lighten their skin and to remove make up, and for maintaining their much admired pale, porcelain complexion. According to an interview we conducted in January 2011 with the staff of Hyakuske, a two-hundred year old cosmetic shop in the Asakusa district of Tokyo, the use of Uguisu-no-Fun was already popular during the mid-Edo period (1603-1868.) Much has been written on wonders of Uguisu-no-Fun as a traditional Japanese facial treatment. The first modern written mention of the use of Uguisu-no-Fun is in a book entitled Shunkin-sho (Portrait of lady Shunkin) published in 1933 by Junichiro Tanizaki, set in Japan's Meiji period (1868-1912.) The main ingredient in Uguisu-no-Fun is a natural compound called Guanine. It is one of the four molecules which form the rungs of the DNA helix (it is the "G" molecule in the "ATGC" sequence.) One of the key compounds for damaged skin DNA repair is a guanine derived enzyme called OGG1 (8-Oxo-Guanine Glycosylase). In clinical studies OGG1 has been demonstrated to treat skin damage caused by UV exposure. OGG1 is used by the leading cosmetic manufacturer in their high end skin care products. REFERENCES: € Textbook of Aging Skin - Farage, Miranda A.; Miller, Kenneth W.; Maibach, Howard I. (Eds.) ISBN: 978-3-540-89655-5 € Topical treatment with OGG1 enzyme affects UVB-induced skin carcinogenesis - Wulff BC, Schick JS, Thomas-Ahner JM, Kusewitt DF, Yarosh DB, Oberyszyn TM. Department of Pathology, The Ohio State University, Columbus, OH, USA.